Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NSD2 | O96028 | 2/20 | 0.38 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.36 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.35 |
| ▸ | GPR119 | Q8TDV5 | 5/20 | 0.35 |
| ▸ | TBK1 | Q9UHD2 | 4/20 | 0.35 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.35 |
| ▸ | LRRK2 | Q5S007 | 3/20 | 0.34 |
| ▸ | ALK | Q9UM73 | 2/20 | 0.34 |
| ▸ | DNMT3A | Q9Y6K1 | 1/20 | 0.34 |
| ▸ | CDK4 | P11802 | 1/20 | 0.33 |
| ▸ | CCND1 | P24385 | 1/20 | 0.33 |
| ▸ | CCND3 | P30281 | 1/20 | 0.33 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.33 |
| ▸ | CFTR | P13569 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31639307 | 0.89 | TBK1 (0.38) | NSD2PIK3CDEHMT2GPR119TBK1 | |
| SCHEMBL31639304 | 0.82 | NRAS (0.39) | LRRK2 | |
| SCHEMBL31639210 | 0.81 | USP30 (0.38) | NSD2PIK3CDALKDNMT3ACDK4 | |
| SCHEMBL30698310 | 0.79 | ALK (0.35) | NSD2PIK3CDGPR119ALKDNMT3A | |
| SCHEMBL31639374 | 0.78 | PIK3CD (0.43) | NSD2PIK3CDEHMT2GPR119TBK1 | |
| SCHEMBL31739613 | 0.78 | ALK (0.35) | NSD2PIK3CDEHMT2ALKDNMT3A | |
| SCHEMBL31639179 | 0.77 | PIK3CD (0.42) | NSD2PIK3CDEHMT2GPR119ALK | |
| SCHEMBL30698314 | 0.76 | ALK (0.34) | NSD2PIK3CDEHMT2LRRK2ALK | |
| SCHEMBL31639084 | 0.76 | CDK4 (0.36) | NSD2PIK3CDGPR119ALKDNMT3A | |
| SCHEMBL30698359 | 0.75 | ALK (0.35) | NSD2PIK3CDEHMT2ALKDNMT3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025137567-A1 | MULTI-CYCLIC IRAK AND FLT3 INHIBITING COMPOUNDS AND USES THEREOF | CHILDREN'S HOSPITAL MEDICAL CENTER (US) | 2025-06-26 | — | — | WO | disclosed |