Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 3/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | KIF11 | P52732 | 1/20 | 0.39 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.38 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | SCN10A | Q9Y5Y9 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL84428 | 0.83 | ALDH1A1 (0.65) | PDE2AALDH1A1SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL2056155 | 0.83 | PDE2A (0.58) | PDE2AALDH1A1SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL19314070 | 0.81 | ACACB (0.44) | PDE2AALDH1A1SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL1676518 | 0.79 | PDE2A (0.54) | PDE2AALDH1A1SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL18291828 | 0.79 | PDE2A (0.54) | PDE2AALDH1A1SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL2021163 | 0.79 | PDE2A (0.54) | PDE2AALDH1A1SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL3310194 | 0.79 | PDE2A (0.54) | PDE2AALDH1A1SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL1729345 | 0.79 | PDE2A (0.54) | PDE2AALDH1A1SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL5924733 | 0.79 | PDE2A (0.54) | PDE2AALDH1A1SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL1046494 | 0.79 | PDE2A (0.54) | PDE2AALDH1A1SLC6A4SLC6A3SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230203062-A1 | THERAPEUTIC COMPOUNDS AND METHODS OF USE | GENENTECH, INC. (US) | 2023-06-29 | — | — | US | disclosed |
| US-10858338-B2 | Inhibitors for soluble epoxide hydrolase (SEH) and fatty acid amide hydrolase (FAAH) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2020-12-08 | — | — | US | disclosed |
| US-10407392-B2 | Antifungal compound process | Mycovia Pharmaceuticals, Inc. (US) | 2019-09-10 | — | — | US | disclosed |
| US-20190177298-A1 | Antifungal Compound Process | MYCOVIA PHARMACEUTICALS INC (US) | 2019-06-13 | — | — | US | disclosed |
| US-20190077785-A1 | INHIBITORS FOR SOLUBLE EPOXIDE HYDROLASE (SEH) AND FATTY ACID AMIDE HYDROLASE (FAAH) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2019-03-14 | — | — | US | disclosed |
| US-20170304272-A1 | ISOXAZOLE DERIVATIVES AS FXR AGONISTS AND METHODS OF USE THEREOF | ENANTA PHARMACEUTICALS, INC. | 2017-10-26 | — | — | US | disclosed |
| EP-1341534-B1 | COMPOUNDS HAVING FUNGICIDAL ACTIVITY AND PROCESSES TO MAKE AND USE SAME | DOW AGROSCIENCES LLC (US) | 2010-03-31 | — | — | EP | disclosed |
| EP-1341534-A4 | COMPOUNDS HAVING FUNGICIDAL ACTIVITY AND PROCESSES TO MAKE AND USE SAME | DOW AGROSCIENCES LLC (US) | 2005-09-28 | — | — | EP | disclosed |
| US-6815556-B2 | KILLING PLANT DISEASES | DOW AGROSCIENCES LLC | 2004-11-09 | — | — | US | disclosed |
| US-20040030189-A1 | Compounds having fungicidal activity and processes to make and use same | RASMUSSEN KLITTICH CARLA JEAN (US) | 2004-02-12 | — | — | US | disclosed |
| EP-1341534-A2 | COMPOUNDS HAVING FUNGICIDAL ACTIVITY AND PROCESSES TO MAKE AND USE SAME | Dow AgroSciences LLC (US) | 2003-09-10 | — | — | EP | disclosed |
| WO-2002040431-A2 | COMPOUNDS HAVING FUNGICIDAL ACTIVITY AND PROCESSES TO MAKE AND USE SAME | DOW AGROSCIENCES LLC (US) | 2002-05-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230203062-A1 | THERAPEUTIC COMPOUNDS AND METHODS OF USE | VHL, TP53, MCL1 | PDE2A 1863/4885ALDH1A1 829/4885SLC6A4 3261/4885 |
| US-10407392-B2 | Antifungal compound process | ERG28, DPM1, CYP51A1 | PDE2A 3677/4885ALDH1A1 1891/4885SLC6A4 3155/4885 |
| US-10858338-B2 | Inhibitors for soluble epoxide hydrolase (SEH) and fatty acid amide hydrolase (FAAH) | FAAH, FAAH2, EPHX2 | PDE2A 2169/4885ALDH1A1 261/4885SLC6A4 1808/4885 |
| US-20040030189-A1 | Compounds having fungicidal activity and processes to make and use same | CYP51A1, DDT, CYP4X1 | PDE2A 949/4885ALDH1A1 315/4885SLC6A4 3644/4885 |
| US-20190177298-A1 | Antifungal Compound Process | ERG28, DPM1, CYP51A1 | PDE2A 3677/4885ALDH1A1 1891/4885SLC6A4 3155/4885 |
| US-20170304272-A1 | ISOXAZOLE DERIVATIVES AS FXR AGONISTS AND METHODS OF USE THEREOF | FXR1, SLC10A1, NR1H4 | PDE2A 1064/4885ALDH1A1 1135/4885SLC6A4 1011/4885 |
| US-20190077785-A1 | INHIBITORS FOR SOLUBLE EPOXIDE HYDROLASE (SEH) AND FATTY ACID AMIDE HYDROLASE (FAAH) | FAAH, FAAH2, EPHX2 | PDE2A 2169/4885ALDH1A1 261/4885SLC6A4 1808/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.