Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | TACR1 | P25103 | 1/20 | 0.33 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.33 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | F2R | P25116 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31649329 | 0.86 | KMT2A (0.41) | KMT2AEPHX2DPP7ALDH1A1LMNA | |
| SCHEMBL31649111 | 0.84 | EPHX2 (0.34) | KMT2AEPHX2ALDH1A1ABCB1MEN1 | |
| SCHEMBL31649064 | 0.82 | DPP7 (0.42) | KMT2AEPHX2DPP7ALDH1A1LMNA | |
| SCHEMBL31649352 | 0.79 | ALDH1A1 (0.43) | KMT2AEPHX2ALDH1A1MEN1 | |
| SCHEMBL31649298 | 0.76 | ALDH1A1 (0.38) | KMT2AALDH1A1LMNAMEN1TSHR | |
| SCHEMBL31649410 | 0.76 | KMT2A (0.45) | KMT2ADPP7ALDH1A1LMNAMEN1 | |
| SCHEMBL31649178 | 0.76 | KMT2A (0.45) | KMT2ADPP7ALDH1A1LMNAMEN1 | |
| SCHEMBL31649428 | 0.75 | KMT2A (0.45) | KMT2ADPP7ALDH1A1LMNAMEN1 | |
| SCHEMBL31649458 | 0.75 | ALDH1A1 (0.47) | KMT2AEPHX2DPP7ALDH1A1SMN1; SMN2 | |
| SCHEMBL31649429 | 0.72 | CD274 (0.42) | PDCD1CD274SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025132943-A1 | DECAHYDROQUINOLINES AS DNA POLYMERASE THETA INHIBITORS | BREAKPOINT THERAPEUTICS GMBH (DE) | 2025-06-26 | — | — | WO | disclosed |