Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD274 | Q9NZQ7 | 17/20 | 0.42 |
| ▸ | PDCD1 | Q15116 | 13/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | PDCD1LG2 | Q9BQ51 | 3/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31649352 | 0.79 | ALDH1A1 (0.43) | — | |
| SCHEMBL31649084 | 0.79 | HSD11B1 (0.32) | NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL31649458 | 0.78 | ALDH1A1 (0.47) | NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL31649298 | 0.75 | ALDH1A1 (0.38) | RAB9ASMN1; SMN2 | |
| SCHEMBL31649033 | 0.72 | KMT2A (0.36) | CD274PDCD1SMN1; SMN2 | |
| SCHEMBL31649410 | 0.70 | KMT2A (0.45) | SMN1; SMN2 | |
| SCHEMBL31649178 | 0.70 | KMT2A (0.45) | — | |
| SCHEMBL31649428 | 0.70 | KMT2A (0.45) | — | |
| SCHEMBL20999801 | 0.65 | CD274 (0.65) | CD274PDCD1PDCD1LG2 | |
| SCHEMBL20999511 | 0.64 | CD274 (0.61) | CD274PDCD1PDCD1LG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025132943-A1 | DECAHYDROQUINOLINES AS DNA POLYMERASE THETA INHIBITORS | BREAKPOINT THERAPEUTICS GMBH (DE) | 2025-06-26 | — | — | WO | disclosed |