Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.47 |
| ▸ | DPP4 | P27487 | 2/20 | 0.44 |
| ▸ | FAP | Q12884 | 1/20 | 0.44 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.44 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.44 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.42 |
| ▸ | MMP1 | P03956 | 1/20 | 0.41 |
| ▸ | MMP13 | P45452 | 1/20 | 0.41 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31649352 | 0.84 | ALDH1A1 (0.43) | ALDH1A1HSD11B1EPHX2KMT2A | |
| SCHEMBL31649309 | 0.83 | ACHE (0.43) | ALDH1A1HRH3KMT2A | |
| SCHEMBL31649298 | 0.80 | ALDH1A1 (0.38) | ALDH1A1RAB9ASMN1; SMN2KMT2AHPGD | |
| SCHEMBL31649429 | 0.78 | CD274 (0.42) | NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL31649339 | 0.76 | DPP4 (0.42) | ALDH1A1HRH3DPP4FAPDPP8 | |
| SCHEMBL31649178 | 0.75 | KMT2A (0.45) | ALDH1A1DPP7KMT2A | |
| SCHEMBL31649410 | 0.75 | KMT2A (0.45) | ALDH1A1DPP7SMN1; SMN2KMT2AGAA | |
| SCHEMBL31649428 | 0.74 | KMT2A (0.45) | ALDH1A1DPP4FAPDPP8DPP9 | |
| SCHEMBL770444 | 0.74 | ALDH1A1 (0.51) | ALDH1A1HRH3DPP4PKMNPC1 | |
| SCHEMBL25260132 | 0.72 | ALDH1A1 (0.46) | ALDH1A1PKMNPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025132943-A1 | DECAHYDROQUINOLINES AS DNA POLYMERASE THETA INHIBITORS | BREAKPOINT THERAPEUTICS GMBH (DE) | 2025-06-26 | — | — | WO | disclosed |