Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.41 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.41 |
| ▸ | CMA1 | P23946 | 10/20 | 0.40 |
| ▸ | CTSL | P07711 | 1/20 | 0.40 |
| ▸ | CTSB | P07858 | 1/20 | 0.40 |
| ▸ | CTSS | P25774 | 1/20 | 0.40 |
| ▸ | F2 | P00734 | 1/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31649391 | 0.93 | ACE (0.50) | ACEKMT2AKLK5CMA1CTSL | |
| SCHEMBL556735 | 0.77 | KMT2A (0.53) | ACEKMT2ACTSLCTSBCTSS | |
| SCHEMBL31649442 | 0.75 | PRSS1 (0.41) | ACEKMT2APRSS1 | |
| SCHEMBL31649357 | 0.74 | DPP7 (0.40) | ACEKMT2ACACNA1BCTSSF2 | |
| SCHEMBL31649419 | 0.74 | SYK (0.54) | ACECMA1CTSLCTSS | |
| SCHEMBL31649407 | 0.74 | ALDH1A1 (0.41) | KMT2APRSS1 | |
| SCHEMBL31649309 | 0.73 | ACHE (0.43) | KMT2APRSS1 | |
| SCHEMBL31649413 | 0.73 | DPP4 (0.49) | ACEF2PRSS1 | |
| SCHEMBL31649269 | 0.73 | DPP4 (0.49) | ACEF2PRSS1 | |
| SCHEMBL31649055 | 0.73 | ACE (0.46) | ACEKMT2AKLK5CMA1CTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025132943-A1 | DECAHYDROQUINOLINES AS DNA POLYMERASE THETA INHIBITORS | BREAKPOINT THERAPEUTICS GMBH (DE) | 2025-06-26 | — | — | WO | disclosed |