Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TACR1 | P25103 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.40 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.39 |
| ▸ | UBE2M | P61081 | 1/20 | 0.38 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31649309 | 0.90 | ACHE (0.43) | PRSS1TACR1MEN1KMT2AHRH3 | |
| SCHEMBL31649407 | 0.89 | ALDH1A1 (0.41) | PRSS1NPC1RAB9ASMN1; SMN2TACR1 | |
| SCHEMBL31649336 | 0.86 | TACR1 (0.47) | NPC1RAB9ASMN1; SMN2TACR1MEN1 | |
| SCHEMBL31649444 | 0.83 | BCHE (0.41) | NPC1RAB9ASMN1; SMN2TACR1HSD11B1 | |
| SCHEMBL31649221 | 0.81 | HSD11B1 (0.40) | NPC1RAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL31649427 | 0.81 | ALDH1A1 (0.46) | NPC1TACR1MEN1KMT2ALMNA | |
| SCHEMBL31649113 | 0.80 | TACR1 (0.39) | TACR1MEN1KMT2APRMT5WDR77 | |
| SCHEMBL31649413 | 0.79 | DPP4 (0.49) | PRSS1NPC1RAB9ASMN1; SMN2TACR1 | |
| SCHEMBL31649269 | 0.79 | DPP4 (0.49) | PRSS1NPC1RAB9ASMN1; SMN2TACR1 | |
| SCHEMBL31649391 | 0.79 | ACE (0.50) | PRSS1KMT2AACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025132943-A1 | DECAHYDROQUINOLINES AS DNA POLYMERASE THETA INHIBITORS | BREAKPOINT THERAPEUTICS GMBH (DE) | 2025-06-26 | — | — | WO | disclosed |