Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 9/20 | 0.49 |
| ▸ | DPP8 | Q6V1X1 | 8/20 | 0.47 |
| ▸ | DPP7 | Q9UHL4 | 7/20 | 0.47 |
| ▸ | DPP9 | Q86TI2 | 5/20 | 0.47 |
| ▸ | FAP | Q12884 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.43 |
| ▸ | CPT2 | P23786 | 1/20 | 0.40 |
| ▸ | CPT1A | P50416 | 1/20 | 0.40 |
| ▸ | ACE | P12821 | 1/20 | 0.40 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.39 |
| ▸ | TACR1 | P25103 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31649269 | 1.00 | DPP4 (0.49) | DPP4DPP8DPP7DPP9FAP | |
| SCHEMBL31649359 | 0.81 | DPP7 (0.55) | DPP4DPP8DPP7DPP9FAP | |
| SCHEMBL31649221 | 0.79 | HSD11B1 (0.40) | NPC1RAB9ASMN1; SMN2HSD11B1CPT2 | |
| SCHEMBL31649442 | 0.79 | PRSS1 (0.41) | NPC1RAB9ASMN1; SMN2HSD11B1ACE | |
| SCHEMBL31649309 | 0.79 | ACHE (0.43) | PRSS1TACR1 | |
| SCHEMBL31649151 | 0.79 | ACHE (0.43) | DPP4DPP8DPP7DPP9FAP | |
| SCHEMBL31649462 | 0.79 | ACHE (0.43) | DPP4DPP8DPP7DPP9FAP | |
| SCHEMBL31649391 | 0.78 | ACE (0.50) | ACEF2PRSS1 | |
| SCHEMBL31369476 | 0.72 | ALPI (0.55) | NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL31323977 | 0.72 | ALPI (0.55) | NPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025132943-A1 | DECAHYDROQUINOLINES AS DNA POLYMERASE THETA INHIBITORS | BREAKPOINT THERAPEUTICS GMBH (DE) | 2025-06-26 | — | — | WO | disclosed |