Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CCR5 | P51681 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | CCR1 | P32246 | 1/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.39 |
| ▸ | APP | P05067 | 1/20 | 0.39 |
| ▸ | TACR1 | P25103 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31649407 | 0.91 | ALDH1A1 (0.41) | ALDH1A1HRH3MEN1KMT2APRSS1 | |
| SCHEMBL31649442 | 0.90 | PRSS1 (0.41) | HRH3MEN1KMT2APRSS1TACR1 | |
| SCHEMBL31649427 | 0.88 | ALDH1A1 (0.46) | ALDH1A1POLBMEN1KMT2ATACR1 | |
| SCHEMBL31649113 | 0.88 | TACR1 (0.39) | ALDH1A1POLBMEN1KMT2ATACR1 | |
| SCHEMBL31649336 | 0.84 | TACR1 (0.47) | MEN1KMT2ATACR1 | |
| SCHEMBL31649458 | 0.83 | ALDH1A1 (0.47) | ALDH1A1HRH3KMT2A | |
| SCHEMBL31649151 | 0.82 | ACHE (0.43) | ACHECCR5OPRM1CCR1HTT | |
| SCHEMBL31649462 | 0.82 | ACHE (0.43) | ACHECCR5OPRM1CCR1HTT | |
| SCHEMBL31649413 | 0.79 | DPP4 (0.49) | PRSS1TACR1 | |
| SCHEMBL31649269 | 0.79 | DPP4 (0.49) | PRSS1TACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025132943-A1 | DECAHYDROQUINOLINES AS DNA POLYMERASE THETA INHIBITORS | BREAKPOINT THERAPEUTICS GMBH (DE) | 2025-06-26 | — | — | WO | disclosed |