SCHEMBL31652878

SCHEMBL31652878

CC[C@]1(CO)O[C@@H](n2cnc3c(N)ncnc32)[C@@H](F)[C@@H]1O

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ADORA3 P0DMS8 4/20 0.52
▸ ADORA2A P29274 3/20 0.52
▸ PI4KA P42356 2/20 0.52
▸ PI4K2B Q8TCG2 2/20 0.52
▸ PI4K2A Q9BTU6 2/20 0.52
▸ PI4KB Q9UBF8 2/20 0.52
▸ ADORA2B P29275 2/20 0.52
▸ ADORA1 P30542 2/20 0.52
▸ DPP4 P27487 1/20 0.52
▸ MEN1 O00255 1/20 0.52
▸ SLC28A1 O00337 1/20 0.52
▸ MAP3K7 O43318 1/20 0.52
▸ SLC28A2 O43868 1/20 0.52
▸ GAPDH P04406 1/20 0.52
▸ MAPK1 P28482 1/20 0.52
▸ STAT6 P42226 1/20 0.52
▸ KMT2A Q03164 1/20 0.52
▸ SMN1; SMN2 Q16637 1/20 0.52
▸ DOT1L Q8TEK3 1/20 0.52
▸ SLC29A1 Q99808 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15070706 1.00 ADORA3 (0.52) ADORA3ADORA2API4KAPI4K2BPI4K2A
SCHEMBL16373916 0.90 ADORA3 (0.54) ADORA3ADORA2API4KAPI4K2BPI4K2A
SCHEMBL16374026 0.90 ADORA3 (0.54) ADORA3ADORA2API4KAPI4K2BPI4K2A
SCHEMBL15070711 0.90 ADORA3 (0.53) ADORA3ADORA2API4KAPI4K2BPI4K2A
SCHEMBL15070701 0.89 AHCY (0.54) ADORA3ADORA2API4KAPI4K2BPI4K2A
SCHEMBL31652766 0.89 PRMT5 (0.59) ADORA3ADORA2API4KAPI4K2BPI4K2A
SCHEMBL31652943 0.89 PRMT5 (0.59) ADORA3ADORA2API4KAPI4K2BPI4K2A
SCHEMBL16573481 0.86 HSP90B1 (0.48) ADORA3ADORA2AADORA2BADORA1SLC29A1
SCHEMBL25394467 0.85 NT5E (0.55) ADORA3ADORA2AADORA2BADORA1AHCY
SCHEMBL15964775 0.85 ADORA2A (0.45) ADORA3ADORA2AADORA2BADORA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260035403-A1 NUCLEOSIDE LINE-1 INHIBITORS TRANSPOSON THERAPEUTICS, INC. (US) 2026-02-05 — — US disclosed
US-20250215039-A1 NUCLEOSIDES FOR TREATING CANCER PRIMEFOUR THERAPEUTICS INC (US) 2025-07-03 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260035403-A1 NUCLEOSIDE LINE-1 INHIBITORS L3MBTL1, TDP1, TRDMT1 ADORA3 1252/4885ADORA2A 1443/4885PI4KA 3457/4885
US-20250215039-A1 NUCLEOSIDES FOR TREATING CANCER UNG, OGG1, NTPCR ADORA3 438/4885ADORA2A 260/4885PI4KA 3457/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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