Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | GPR119 | Q8TDV5 | 7/20 | 0.46 |
| ▸ | ALK | Q9UM73 | 5/20 | 0.44 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.44 |
| ▸ | NAMPT | P43490 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.42 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31661161 | 0.83 | GPR119 (0.39) | MAPTLMNAALDH1A1GPR119SMN1; SMN2 | |
| SCHEMBL31661173 | 0.81 | ALDH1A1 (0.42) | MAPTLMNAALDH1A1GPR119NAMPT | |
| SCHEMBL20722608 | 0.77 | MAPT (0.48) | MAPTLMNAALDH1A1GPR119ALK | |
| SCHEMBL20731008 | 0.77 | MAPT (0.48) | MAPTLMNAALDH1A1GPR119ALK | |
| SCHEMBL30061346 | 0.77 | MAPT (0.48) | MAPTLMNAALDH1A1GPR119ALK | |
| SCHEMBL3846632 | 0.76 | SCD5 (0.58) | MAPTLMNAALDH1A1GPR119PDK2 | |
| SCHEMBL31704181 | 0.75 | BACE1 (0.42) | MAPTLMNAALDH1A1GPR119 | |
| SCHEMBL20722911 | 0.75 | GPR119 (0.47) | MAPTLMNAALDH1A1GPR119ALK | |
| SCHEMBL20731006 | 0.75 | GPR119 (0.47) | MAPTLMNAALDH1A1GPR119ALK | |
| SCHEMBL30062539 | 0.75 | GPR119 (0.47) | MAPTLMNAALDH1A1GPR119ALK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025151602-A1 | HETEROARYL COMPOUNDS AS LIGAND DIRECTED DEGRADERS OF IRAK4 | BRISTOL-MYERS SQUIBB COMPANY (US) | 2025-07-17 | — | — | WO | disclosed |