Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.41 |
| ▸ | NAMPT | P43490 | 1/20 | 0.41 |
| ▸ | BACE1 | P56817 | 4/20 | 0.40 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.39 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.39 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.39 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.39 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.39 |
| ▸ | CKS1B | P61024 | 1/20 | 0.39 |
| ▸ | SKP1 | P63208 | 1/20 | 0.39 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.39 |
| ▸ | STS | P08842 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31661184 | 0.81 | MAPT (0.47) | ALDH1A1GPR119MAPTLMNANAMPT | |
| SCHEMBL31661161 | 0.79 | GPR119 (0.39) | ALDH1A1GPR119MAPTLMNAPTPN2 | |
| SCHEMBL21198677 | 0.75 | ADRB1 (0.52) | ALDH1A1LMNAMAPK1 | |
| SCHEMBL12478533 | 0.75 | DRD2 (0.50) | — | |
| SCHEMBL5366208 | 0.74 | NAMPT (0.47) | ALDH1A1GPR119MAPTLMNANAMPT | |
| SCHEMBL5369055 | 0.72 | HTR1A (0.46) | ALDH1A1GPR119MAPTLMNANAMPT | |
| SCHEMBL1439591 | 0.72 | GPR119 (0.44) | ALDH1A1GPR119MAPTLMNANAMPT | |
| SCHEMBL23980816 | 0.72 | MEN1 (0.47) | BACE1STSHTT | |
| SCHEMBL114482 | 0.71 | GPR119 (0.53) | ALDH1A1GPR119MAPTLMNAPTPN2 | |
| SCHEMBL30659464 | 0.71 | MAPK1 (0.50) | ALDH1A1GPR119MAPTLMNANAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025151602-A1 | HETEROARYL COMPOUNDS AS LIGAND DIRECTED DEGRADERS OF IRAK4 | BRISTOL-MYERS SQUIBB COMPANY (US) | 2025-07-17 | — | — | WO | disclosed |