Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 2/20 | 0.37 |
| ▸ | SRC | P12931 | 1/20 | 0.36 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.35 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.35 |
| ▸ | AR | P10275 | 1/20 | 0.35 |
| ▸ | JAK2 | O60674 | 2/20 | 0.34 |
| ▸ | JAK1 | P23458 | 2/20 | 0.34 |
| ▸ | PARP1 | P09874 | 2/20 | 0.34 |
| ▸ | TNK2 | Q07912 | 2/20 | 0.34 |
| ▸ | TNK1 | Q13470 | 2/20 | 0.34 |
| ▸ | NSD2 | O96028 | 1/20 | 0.34 |
| ▸ | TYK2 | P29597 | 1/20 | 0.34 |
| ▸ | JAK3 | P52333 | 1/20 | 0.34 |
| ▸ | DDR1 | Q08345 | 2/20 | 0.34 |
| ▸ | CXCR4 | P61073 | 3/20 | 0.33 |
| ▸ | METAP2 | P50579 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31661374 | 0.89 | CHKA (0.41) | HTR6SRC | |
| SCHEMBL31661381 | 0.86 | KCNH2 (0.33) | KCNH2MCHR1JAK2JAK1PARP1 | |
| SCHEMBL31661309 | 0.85 | KCNH2 (0.34) | KCNH2MCHR1JAK2JAK1TYK2 | |
| SCHEMBL31661357 | 0.85 | RET (0.36) | SRCKCNH2MCHR1 | |
| SCHEMBL31661366 | 0.82 | NSD2 (0.43) | KCNH2NSD2 | |
| SCHEMBL30961809 | 0.81 | HTR6 (0.40) | HTR6KCNH2MCHR1PARP1CXCR4 | |
| SCHEMBL31661387 | 0.81 | MELK (0.35) | SRCARMETAP2 | |
| SCHEMBL31661361 | 0.79 | CHKA (0.43) | HTR6SRCKCNH2METAP2 | |
| SCHEMBL31661349 | 0.79 | METAP2 (0.36) | SRCARMETAP2 | |
| SCHEMBL31661369 | 0.76 | PTGER4 (0.37) | METAP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025151549-A1 | PYRIDO[3,2-B]INDOLE-3-CARBONITRILE COMPOUNDS AND COMPOSITION FOR TARGETING TP53-Y220C MUTANTS | FLARE THERAPEUTICS INC. (US) | 2025-07-17 | — | — | WO | disclosed |