Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHKA | P35790 | 2/20 | 0.41 |
| ▸ | SRC | P12931 | 10/20 | 0.39 |
| ▸ | FYN | P06241 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | HTR6 | P50406 | 3/20 | 0.39 |
| ▸ | TNIK | Q9UKE5 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | ABL1 | P00519 | 1/20 | 0.36 |
| ▸ | ABL2 | P42684 | 1/20 | 0.36 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.36 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31661361 | 0.90 | CHKA (0.43) | CHKASRCFYNCNR2HTR6 | |
| SCHEMBL31661357 | 0.90 | RET (0.36) | CHKASRC | |
| SCHEMBL31661341 | 0.89 | HTR6 (0.37) | SRCHTR6 | |
| SCHEMBL31661366 | 0.85 | NSD2 (0.43) | TP53MAPT | |
| SCHEMBL31661381 | 0.84 | KCNH2 (0.33) | — | |
| SCHEMBL31661387 | 0.84 | MELK (0.35) | SRCPRKCQPRKCD | |
| SCHEMBL31661309 | 0.83 | KCNH2 (0.34) | — | |
| SCHEMBL30961876 | 0.81 | CNR2 (0.42) | CHKACNR2HTR6TP53MAPT | |
| SCHEMBL31661349 | 0.79 | METAP2 (0.36) | SRC | |
| SCHEMBL30961763 | 0.78 | CNR2 (0.43) | CHKACNR2HTR6TP53MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025151549-A1 | PYRIDO[3,2-B]INDOLE-3-CARBONITRILE COMPOUNDS AND COMPOSITION FOR TARGETING TP53-Y220C MUTANTS | FLARE THERAPEUTICS INC. (US) | 2025-07-17 | — | — | WO | disclosed |