Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MELK | Q14680 | 1/20 | 0.35 |
| ▸ | METAP2 | P50579 | 4/20 | 0.34 |
| ▸ | SRC | P12931 | 9/20 | 0.32 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.32 |
| ▸ | LYN | P07948 | 3/20 | 0.31 |
| ▸ | PRKCQ | Q04759 | 3/20 | 0.31 |
| ▸ | PRKCD | Q05655 | 3/20 | 0.31 |
| ▸ | PRKCB | P05771 | 1/20 | 0.31 |
| ▸ | LCK | P06239 | 1/20 | 0.31 |
| ▸ | PRKCH | P24723 | 1/20 | 0.31 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.31 |
| ▸ | PGR | P06401 | 1/20 | 0.31 |
| ▸ | AR | P10275 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31661374 | 0.84 | CHKA (0.41) | SRCPRKCQPRKCD | |
| SCHEMBL31661349 | 0.83 | METAP2 (0.36) | METAP2SRCPGRAR | |
| SCHEMBL31661339 | 0.82 | CAMK2D (0.37) | MELKMETAP2CAMK2D | |
| SCHEMBL31661388 | 0.81 | CAMK2D (0.42) | MELKMETAP2CAMK2D | |
| SCHEMBL31661341 | 0.81 | HTR6 (0.37) | METAP2SRCAR | |
| SCHEMBL31661369 | 0.80 | PTGER4 (0.37) | METAP2 | |
| SCHEMBL30961799 | 0.79 | CAMK2D (0.33) | CAMK2D | |
| SCHEMBL31661381 | 0.79 | KCNH2 (0.33) | METAP2 | |
| SCHEMBL31661359 | 0.77 | METAP2 (0.35) | METAP2 | |
| SCHEMBL30961807 | 0.76 | CAMK2D (0.33) | METAP2CAMK2D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025151549-A1 | PYRIDO[3,2-B]INDOLE-3-CARBONITRILE COMPOUNDS AND COMPOSITION FOR TARGETING TP53-Y220C MUTANTS | FLARE THERAPEUTICS INC. (US) | 2025-07-17 | — | — | WO | disclosed |