Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 6/20 | 0.36 |
| ▸ | PIK3R1 | P27986 | 2/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | SRC | P12931 | 1/20 | 0.31 |
| ▸ | AR | P10275 | 2/20 | 0.31 |
| ▸ | PGR | P06401 | 1/20 | 0.31 |
| ▸ | RORA | P35398 | 1/20 | 0.31 |
| ▸ | RORC | P51449 | 1/20 | 0.31 |
| ▸ | RORB | Q92753 | 1/20 | 0.31 |
| ▸ | EGFR | P00533 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31661359 | 0.86 | METAP2 (0.35) | METAP2 | |
| SCHEMBL31661369 | 0.84 | PTGER4 (0.37) | METAP2RORARORCRORB | |
| SCHEMBL31661387 | 0.83 | MELK (0.35) | METAP2SRCARPGR | |
| SCHEMBL31661374 | 0.79 | CHKA (0.41) | SRC | |
| SCHEMBL31661341 | 0.79 | HTR6 (0.37) | METAP2SRCAR | |
| SCHEMBL31661330 | 0.79 | METAP2 (0.33) | METAP2 | |
| SCHEMBL31661323 | 0.79 | METAP2 (0.35) | METAP2 | |
| SCHEMBL31661381 | 0.77 | KCNH2 (0.33) | METAP2 | |
| SCHEMBL31661309 | 0.77 | KCNH2 (0.34) | METAP2 | |
| SCHEMBL30961771 | 0.72 | NT5E (0.35) | METAP2SMN1; SMN2RORARORCRORB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025151549-A1 | PYRIDO[3,2-B]INDOLE-3-CARBONITRILE COMPOUNDS AND COMPOSITION FOR TARGETING TP53-Y220C MUTANTS | FLARE THERAPEUTICS INC. (US) | 2025-07-17 | — | — | WO | disclosed |