Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KRAS | P01116 | 8/20 | 0.59 |
| ▸ | SOS1 | Q07889 | 2/20 | 0.52 |
| ▸ | USP1 | O94782 | 6/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 4/20 | 0.31 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.31 |
| ▸ | HSD11B2 | P80365 | 1/20 | 0.31 |
| ▸ | BACE1 | P56817 | 1/20 | 0.31 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.31 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31661745 | 0.78 | KRAS (0.35) | KRASSOS1USP1SCN9A | |
| SCHEMBL31661747 | 0.78 | KRAS (0.35) | KRASSOS1USP1SCN9A | |
| SCHEMBL31661808 | 0.76 | KRAS (0.45) | KRASSOS1SCN9A | |
| SCHEMBL31661613 | 0.75 | GRM5 (0.40) | USP1 | |
| SCHEMBL26287232 | 0.74 | KRAS (1.00) | KRASSOS1 | |
| SCHEMBL31661633 | 0.73 | CHUK (0.34) | USP1SCN9A | |
| SCHEMBL25763759 | 0.71 | KRAS (0.63) | KRASSOS1 | |
| SCHEMBL25763213 | 0.69 | KRAS (0.61) | KRASSOS1 | |
| SCHEMBL25768152 | 0.69 | KRAS (0.61) | KRASSOS1 | |
| SCHEMBL25763578 | 0.68 | KRAS (0.66) | KRASSOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025151705-A1 | NOVEL INHIBITORS OF DNA DAMAGE REPAIR PATHWAY | VRISE THERAPEUTICS, INC. (US) | 2025-07-17 | — | — | WO | claimed |
| WO-2025151705-A1 | NOVEL INHIBITORS OF DNA DAMAGE REPAIR PATHWAY | VRISE THERAPEUTICS, INC. (US) | 2025-07-17 | — | — | WO | disclosed |