Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 10/20 | 0.40 |
| ▸ | USP1 | O94782 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31661747 | 0.83 | KRAS (0.35) | GRM5USP1LMNAGAAHTT | |
| SCHEMBL31661745 | 0.83 | KRAS (0.35) | GRM5USP1LMNAGAAHTT | |
| SCHEMBL31661616 | 0.75 | KRAS (0.59) | USP1 | |
| SCHEMBL31661633 | 0.72 | CHUK (0.34) | USP1LMNASMN1; SMN2NPC1RAB9A | |
| SCHEMBL31661659 | 0.67 | LMNA (0.55) | LMNAHTTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL31661744 | 0.63 | NR1H4 (0.50) | LMNASMN1; SMN2NPC1RAB9A | |
| SCHEMBL31661762 | 0.63 | NR1H4 (0.50) | LMNASMN1; SMN2NPC1RAB9A | |
| SCHEMBL18865809 | 0.63 | CYP11B2 (0.47) | USP1GAA | |
| SCHEMBL25431072 | 0.62 | PTGS2 (0.44) | USP1GAANPC1RAB9A | |
| SCHEMBL31661828 | 0.60 | USP1 (0.41) | USP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025151705-A1 | NOVEL INHIBITORS OF DNA DAMAGE REPAIR PATHWAY | VRISE THERAPEUTICS, INC. (US) | 2025-07-17 | — | — | WO | claimed |
| WO-2025151705-A1 | NOVEL INHIBITORS OF DNA DAMAGE REPAIR PATHWAY | VRISE THERAPEUTICS, INC. (US) | 2025-07-17 | — | — | WO | disclosed |