Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KRAS | P01116 | 8/20 | 0.45 |
| ▸ | SOS1 | Q07889 | 2/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.30 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.30 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31661811 | 0.81 | KRAS (0.43) | KRASSCN9AKDM4EALDH1A1MAPT | |
| SCHEMBL31661786 | 0.77 | ADRB2 (0.35) | SCN9AKDM4EALDH1A1HPGDCYP3A4 | |
| SCHEMBL31661616 | 0.76 | KRAS (0.59) | KRASSOS1SCN9A | |
| SCHEMBL31661812 | 0.71 | ADRB2 (0.45) | KDM4EALDH1A1HPGDCYP3A4CYP2D6 | |
| SCHEMBL38652202 | 0.70 | KRAS (0.75) | KRASSOS1KDM4EALDH1A1MAPT | |
| SCHEMBL31328754 | 0.69 | KRAS (0.66) | KRASSOS1KDM4EALDH1A1MAPT | |
| SCHEMBL24091435 | 0.67 | KRAS (0.70) | KRASSOS1KDM4EALDH1A1MAPT | |
| SCHEMBL31661760 | 0.67 | USP1 (0.41) | KDM4EALDH1A1HPGDCYP3A4CYP2D6 | |
| SCHEMBL31661807 | 0.66 | ADRB2 (0.41) | KDM4EALDH1A1HPGDCYP3A4CYP2D6 | |
| SCHEMBL24091569 | 0.65 | KRAS (1.00) | KRASSOS1KDM4EALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025151705-A1 | NOVEL INHIBITORS OF DNA DAMAGE REPAIR PATHWAY | VRISE THERAPEUTICS, INC. (US) | 2025-07-17 | — | — | WO | disclosed |