Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 15/20 | 0.49 |
| ▸ | USP1 | O94782 | 3/20 | 0.42 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31661582 | 0.93 | USP1 (0.46) | S1PR1USP1CA4MEN1NPC1 | |
| SCHEMBL31661551 | 0.81 | NPC1 (0.44) | S1PR1S1PR5MEN1NPC1ALDH1A1 | |
| SCHEMBL31661635 | 0.81 | S1PR1 (0.45) | S1PR1S1PR5NPC1TP53NFKB1 | |
| SCHEMBL31661543 | 0.80 | S1PR1 (0.45) | S1PR1USP1CA4MEN1NPC1 | |
| SCHEMBL31661578 | 0.80 | S1PR1 (0.40) | S1PR1USP1 | |
| SCHEMBL31661565 | 0.79 | THRB (0.47) | S1PR1USP1CA4MEN1NPC1 | |
| SCHEMBL31661590 | 0.79 | NPC1 (0.44) | S1PR1USP1MEN1NPC1TP53 | |
| SCHEMBL31661774 | 0.78 | TP53 (0.51) | S1PR1USP1CA4MEN1NPC1 | |
| SCHEMBL31661691 | 0.77 | S1PR1 (0.38) | S1PR1USP1CA4MEN1NPC1 | |
| SCHEMBL31661641 | 0.76 | S1PR1 (0.46) | S1PR1MEN1NPC1ALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025151705-A1 | NOVEL INHIBITORS OF DNA DAMAGE REPAIR PATHWAY | VRISE THERAPEUTICS, INC. (US) | 2025-07-17 | — | — | WO | claimed |
| WO-2025151705-A1 | NOVEL INHIBITORS OF DNA DAMAGE REPAIR PATHWAY | VRISE THERAPEUTICS, INC. (US) | 2025-07-17 | — | — | WO | disclosed |