Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 17/20 | 0.45 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.36 |
| ▸ | RELA | Q04206 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31661764 | 0.91 | RAB9A (0.43) | S1PR1S1PR3NPC1TP53RAB9A | |
| SCHEMBL31661578 | 0.84 | S1PR1 (0.40) | S1PR1S1PR3 | |
| SCHEMBL31661735 | 0.81 | S1PR1 (0.38) | S1PR1S1PR3S1PR5 | |
| SCHEMBL31661750 | 0.81 | S1PR1 (0.38) | S1PR1S1PR3S1PR5 | |
| SCHEMBL31661551 | 0.81 | NPC1 (0.44) | S1PR1NPC1TP53RAB9ASMN1; SMN2 | |
| SCHEMBL31661646 | 0.81 | S1PR1 (0.49) | S1PR1NPC1TP53RAB9ASMN1; SMN2 | |
| SCHEMBL31661573 | 0.79 | PTGS1 (0.41) | S1PR1NPC1TP53RAB9ASMN1; SMN2 | |
| SCHEMBL31661691 | 0.78 | S1PR1 (0.38) | S1PR1NPC1TP53RAB9ASMN1; SMN2 | |
| SCHEMBL31661641 | 0.77 | S1PR1 (0.46) | S1PR1S1PR3NPC1TP53RAB9A | |
| SCHEMBL31661659 | 0.75 | LMNA (0.55) | S1PR1S1PR3NPC1TP53RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025151705-A1 | NOVEL INHIBITORS OF DNA DAMAGE REPAIR PATHWAY | VRISE THERAPEUTICS, INC. (US) | 2025-07-17 | — | — | WO | claimed |
| WO-2025151705-A1 | NOVEL INHIBITORS OF DNA DAMAGE REPAIR PATHWAY | VRISE THERAPEUTICS, INC. (US) | 2025-07-17 | — | — | WO | disclosed |