Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 0.46 |
| ▸ | S1PR1 | P21453 | 6/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.40 |
| ▸ | NPC1 | O15118 | 4/20 | 0.40 |
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.40 |
| ▸ | ATM | Q13315 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | CASP7 | P55210 | 1/20 | 0.40 |
| ▸ | USP1 | O94782 | 6/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31661587 | 0.84 | SMN1; SMN2 (0.56) | S1PR1KDM4ENPC1RAB9AALDH1A1 | |
| SCHEMBL31661659 | 0.81 | LMNA (0.55) | S1PR1KDM4ENPC1RAB9AALDH1A1 | |
| SCHEMBL31661672 | 0.81 | CHUK (0.44) | S1PR1KDM4ENPC1RAB9AALDH1A1 | |
| SCHEMBL31661753 | 0.77 | S1PR1 (0.42) | S1PR1KDM4ENPC1RAB9AALDH1A1 | |
| SCHEMBL31661762 | 0.77 | NR1H4 (0.50) | S1PR1KDM4ENPC1RAB9AALDH1A1 | |
| SCHEMBL31661744 | 0.77 | NR1H4 (0.50) | S1PR1KDM4ENPC1RAB9AALDH1A1 | |
| SCHEMBL31661798 | 0.75 | CASP3 (0.44) | S1PR1KDM4ENPC1RAB9AALDH1A1 | |
| SCHEMBL31661670 | 0.75 | USP1 (0.54) | USP1 | |
| SCHEMBL31661677 | 0.73 | USP1 (0.52) | S1PR1NPC1RAB9AMAPK1SMN1; SMN2 | |
| SCHEMBL31661828 | 0.71 | USP1 (0.41) | PTGS2USP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025151705-A1 | NOVEL INHIBITORS OF DNA DAMAGE REPAIR PATHWAY | VRISE THERAPEUTICS, INC. (US) | 2025-07-17 | — | — | WO | claimed |
| WO-2025151705-A1 | NOVEL INHIBITORS OF DNA DAMAGE REPAIR PATHWAY | VRISE THERAPEUTICS, INC. (US) | 2025-07-17 | — | — | WO | disclosed |