Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 19/20 | 0.38 |
| ▸ | S1PR3 | Q99500 | 8/20 | 0.34 |
| ▸ | S1PR5 | Q9H228 | 7/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31661750 | 1.00 | S1PR1 (0.38) | S1PR1S1PR3S1PR5KDM4EALDH1A1 | |
| SCHEMBL31661784 | 0.92 | USP1 (0.34) | S1PR1KDM4EALDH1A1CYP3A4CYP2D6 | |
| SCHEMBL31661645 | 0.92 | USP1 (0.34) | S1PR1KDM4EALDH1A1CYP3A4CYP2D6 | |
| SCHEMBL31661635 | 0.81 | S1PR1 (0.45) | S1PR1S1PR3S1PR5 | |
| SCHEMBL31661578 | 0.78 | S1PR1 (0.40) | S1PR1S1PR3 | |
| SCHEMBL31661551 | 0.74 | NPC1 (0.44) | S1PR1S1PR5KDM4EALDH1A1HSD17B10 | |
| SCHEMBL31661646 | 0.74 | S1PR1 (0.49) | S1PR1S1PR5ALDH1A1HSD17B10 | |
| SCHEMBL31661573 | 0.73 | PTGS1 (0.41) | S1PR1 | |
| SCHEMBL31661764 | 0.73 | RAB9A (0.43) | S1PR1S1PR3KDM4E | |
| SCHEMBL31661691 | 0.72 | S1PR1 (0.38) | S1PR1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025151705-A1 | NOVEL INHIBITORS OF DNA DAMAGE REPAIR PATHWAY | VRISE THERAPEUTICS, INC. (US) | 2025-07-17 | — | — | WO | disclosed |