Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | USP1 | O94782 | 16/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.38 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.38 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.38 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31661818 | 0.85 | PTGS2 (0.39) | PTGS2USP1HDAC3HDAC4HDAC1 | |
| SCHEMBL31661812 | 0.83 | ADRB2 (0.45) | PTGS2USP1KDM4EALDH1A1CYP3A4 | |
| SCHEMBL25255920 | 0.79 | USP1 (0.45) | PTGS2USP1HDAC6KDM4EALDH1A1 | |
| SCHEMBL31138700 | 0.79 | PTGS2 (0.44) | PTGS2USP1KDM4EALDH1A1CYP3A4 | |
| SCHEMBL22122022 | 0.78 | ADORA2A (0.46) | PTGS2USP1KDM4EALDH1A1CYP3A4 | |
| SCHEMBL10915635 | 0.78 | PTGS2 (0.44) | PTGS2USP1KDM4EALDH1A1CYP3A4 | |
| SCHEMBL22165856 | 0.78 | PTGS2 (0.44) | PTGS2USP1KDM4E | |
| SCHEMBL31661785 | 0.77 | ALDH1A1 (0.44) | PTGS2USP1HDAC3HDAC4HDAC1 | |
| SCHEMBL31138591 | 0.77 | PTGS2 (0.39) | PTGS2USP1 | |
| SCHEMBL30603218 | 0.77 | USP1 (0.43) | USP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025151705-A1 | NOVEL INHIBITORS OF DNA DAMAGE REPAIR PATHWAY | VRISE THERAPEUTICS, INC. (US) | 2025-07-17 | — | — | WO | disclosed |