Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.44 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.44 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25255920 | 0.83 | USP1 (0.45) | ALDH1A1KDM4ECYP3A4HSD17B10CYP2D6 | |
| SCHEMBL31138700 | 0.83 | PTGS2 (0.44) | ALDH1A1KDM4ECYP3A4HSD17B10CYP2D6 | |
| SCHEMBL22122022 | 0.83 | ADORA2A (0.46) | ALDH1A1KDM4ECYP3A4HSD17B10CYP2D6 | |
| SCHEMBL31661812 | 0.79 | ADRB2 (0.45) | ALDH1A1KDM4ECYP3A4HSD17B10CYP2D6 | |
| SCHEMBL30146258 | 0.79 | KDM4E (0.44) | ALDH1A1KDM4ECYP3A4HSD17B10CYP2D6 | |
| SCHEMBL11622741 | 0.77 | SMN1; SMN2 (0.48) | ALDH1A1KDM4EHSD17B10NPC1GAA | |
| SCHEMBL31661763 | 0.77 | PTGS2 (0.39) | ALDH1A1KDM4ECYP3A4HSD17B10CYP2D6 | |
| SCHEMBL24718540 | 0.77 | RXRA (0.49) | CYP2C9USP1PTGS2 | |
| SCHEMBL25431072 | 0.77 | PTGS2 (0.44) | ALDH1A1KDM4EHSD17B10NPC1GAA | |
| SCHEMBL10915635 | 0.77 | PTGS2 (0.44) | ALDH1A1KDM4ECYP3A4HSD17B10CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025151705-A1 | NOVEL INHIBITORS OF DNA DAMAGE REPAIR PATHWAY | VRISE THERAPEUTICS, INC. (US) | 2025-07-17 | — | — | WO | disclosed |