Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 7/20 | 0.34 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.34 |
| ▸ | SYK | P43405 | 3/20 | 0.33 |
| ▸ | JAK1 | P23458 | 1/20 | 0.33 |
| ▸ | JAK3 | P52333 | 1/20 | 0.33 |
| ▸ | CCNC | P24863 | 1/20 | 0.32 |
| ▸ | CDK8 | P49336 | 1/20 | 0.32 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.32 |
| ▸ | HAO1 | Q9UJM8 | 2/20 | 0.32 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.32 |
| ▸ | KDM1A | O60341 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31661904 | 0.93 | CCNC (0.34) | SCN9AROCK2SYKJAK1JAK3 | |
| SCHEMBL31662291 | 0.92 | NTRK1 (0.38) | SCN9AIRAK4NTRK1KCNH2NTRK2 | |
| SCHEMBL31661958 | 0.91 | LTA4H (0.36) | SCN9AROCK2SYKCCNCCDK8 | |
| SCHEMBL31661896 | 0.90 | KDM1A (0.41) | SCN9AROCK2SYKKDM1A | |
| SCHEMBL31662113 | 0.88 | SCN9A (0.39) | SCN9AROCK2SYKIRAK4HAO1 | |
| SCHEMBL31662354 | 0.86 | SCN9A (0.38) | SCN9AROCK2SYKJAK1JAK3 | |
| SCHEMBL31661890 | 0.85 | NTRK1 (0.37) | SCN9ASYKJAK1JAK3NTRK1 | |
| SCHEMBL31661960 | 0.85 | SCN1A (0.37) | SCN9AROCK2SYKJAK1JAK3 | |
| SCHEMBL31661986 | 0.84 | CHEK2 (0.40) | SCN9AJAK3IRAK4NTRK1KCNH2 | |
| SCHEMBL31661875 | 0.84 | SCN9A (0.40) | SCN9AROCK2SYKIRAK4HAO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025149545-A1 | HETEROARYLPHENYL ETHER DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2025-07-17 | — | — | WO | claimed |
| WO-2025149545-A1 | HETEROARYLPHENYL ETHER DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2025-07-17 | — | — | WO | disclosed |