Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPT1A | P50416 | 4/20 | 0.34 |
| ▸ | ATF4 | P18848 | 1/20 | 0.34 |
| ▸ | ACACB | O00763 | 2/20 | 0.34 |
| ▸ | CPT2 | P23786 | 3/20 | 0.33 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
| ▸ | PARP10 | Q53GL7 | 3/20 | 0.32 |
| ▸ | FPR2 | P25090 | 2/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.32 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.32 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.31 |
| ▸ | PARP15 | Q460N3 | 2/20 | 0.31 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.31 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.31 |
| ▸ | CHEK2 | O96017 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31661914 | 1.00 | CPT1A (0.34) | CPT1AATF4ACACBCPT2TBXAS1 | |
| SCHEMBL31662141 | 1.00 | CPT1A (0.34) | CPT1AATF4ACACBCPT2TBXAS1 | |
| SCHEMBL31662082 | 0.95 | TBXAS1 (0.34) | CPT1ACPT2TBXAS1HRH3PARP10 | |
| SCHEMBL31662398 | 0.86 | BMPR1B (0.34) | CPT1AACACBCPT2CYP11B2 | |
| SCHEMBL31662132 | 0.85 | CPT2 (0.32) | CPT1ACPT2PARP10CYP11B2MAP4K4 | |
| SCHEMBL31662277 | 0.84 | MAPT (0.38) | — | |
| SCHEMBL31662136 | 0.80 | HRH3 (0.42) | CPT1AHRH3 | |
| SCHEMBL31662459 | 0.80 | TBXAS1 (0.40) | TBXAS1HRH3PARP10PARP15OPRM1 | |
| SCHEMBL31662207 | 0.78 | SMN1; SMN2 (0.34) | HRH3PARP10PARP15PARP2OPRM1 | |
| SCHEMBL31662424 | 0.75 | PARP10 (0.48) | PARP10MAP4K4PARP15PARP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025149545-A1 | HETEROARYLPHENYL ETHER DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2025-07-17 | — | — | WO | claimed |
| WO-2025149545-A1 | HETEROARYLPHENYL ETHER DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2025-07-17 | — | — | WO | disclosed |