Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BMPR1B | O00238 | 1/20 | 0.34 |
| ▸ | BMPR1A | P36894 | 1/20 | 0.34 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.34 |
| ▸ | ACVRL1 | P37023 | 1/20 | 0.34 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.34 |
| ▸ | GCK | P35557 | 3/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | HPGDS | O60760 | 1/20 | 0.31 |
| ▸ | ABL1 | P00519 | 1/20 | 0.31 |
| ▸ | CPT2 | P23786 | 1/20 | 0.31 |
| ▸ | CPT1A | P50416 | 1/20 | 0.31 |
| ▸ | TTK | P33981 | 1/20 | 0.31 |
| ▸ | EED | O75530 | 1/20 | 0.31 |
| ▸ | RBBP4 | Q09028 | 1/20 | 0.31 |
| ▸ | SUZ12 | Q15022 | 1/20 | 0.31 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.31 |
| ▸ | AEBP2 | Q6ZN18 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.31 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31662082 | 0.91 | TBXAS1 (0.34) | CPT2CPT1ACYP11B2KDM4EALDH1A1 | |
| SCHEMBL31662277 | 0.89 | MAPT (0.38) | HTTHPGDSKDM4EALDH1A1 | |
| SCHEMBL31661914 | 0.86 | CPT1A (0.34) | CPT2CPT1ACYP11B2ACACB | |
| SCHEMBL31662141 | 0.86 | CPT1A (0.34) | CPT2CPT1ACYP11B2ACACB | |
| SCHEMBL31661907 | 0.86 | CPT1A (0.34) | CPT2CPT1ACYP11B2ACACB | |
| SCHEMBL31662628 | 0.82 | KCNH2 (0.36) | HTTNPC1KDM4EALDH1A1 | |
| SCHEMBL31662132 | 0.81 | CPT2 (0.32) | CPT2CPT1ATTKNPC1CYP11B2 | |
| SCHEMBL31662272 | 0.80 | KCNH2 (0.37) | GCKHTTNPC1ALDH1A1 | |
| SCHEMBL31662623 | 0.79 | MAPT (0.33) | HTTNPC1KDM4EALDH1A1 | |
| SCHEMBL31662464 | 0.78 | MPO (0.41) | HTTNPC1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025149545-A1 | HETEROARYLPHENYL ETHER DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2025-07-17 | — | — | WO | disclosed |