Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 4/20 | 0.40 |
| ▸ | PARP10 | Q53GL7 | 4/20 | 0.39 |
| ▸ | CHEK2 | O96017 | 2/20 | 0.35 |
| ▸ | PARP15 | Q460N3 | 2/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.33 |
| ▸ | PARP16 | Q8N5Y8 | 1/20 | 0.33 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.33 |
| ▸ | PARP4 | Q9UKK3 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31662594 | 0.87 | MAPT (0.45) | ALDH1A1L3MBTL1CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL31662424 | 0.83 | PARP10 (0.48) | PARP10PARP15ALDH1A1KMT2APARP14 | |
| SCHEMBL31662250 | 0.82 | HRH3 (0.46) | HRH3 | |
| SCHEMBL31661965 | 0.82 | SCN9A (0.39) | TBXAS1CHEK2HRH3OPRM1 | |
| SCHEMBL31661860 | 0.82 | POLB (0.42) | HRH3ALDH1A1KMT2AOPRM1OPRD1 | |
| SCHEMBL31662082 | 0.81 | TBXAS1 (0.34) | TBXAS1PARP10CHEK2PARP15HRH3 | |
| SCHEMBL31662147 | 0.81 | CYP11B2 (0.39) | TBXAS1CHEK2HRH3OPRM1OPRD1 | |
| SCHEMBL31662628 | 0.81 | KCNH2 (0.36) | TBXAS1CHEK2ALDH1A1KMT2AL3MBTL1 | |
| SCHEMBL31661907 | 0.80 | CPT1A (0.34) | TBXAS1PARP10CHEK2PARP15HRH3 | |
| SCHEMBL31662141 | 0.80 | CPT1A (0.34) | TBXAS1PARP10CHEK2PARP15HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025149545-A1 | HETEROARYLPHENYL ETHER DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2025-07-17 | — | — | WO | disclosed |