Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 9/20 | 0.48 |
| ▸ | PARP15 | Q460N3 | 4/20 | 0.38 |
| ▸ | PARP14 | Q460N5 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | PARP16 | Q8N5Y8 | 1/20 | 0.38 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.38 |
| ▸ | PARP4 | Q9UKK3 | 1/20 | 0.38 |
| ▸ | F2 | P00734 | 2/20 | 0.37 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.37 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.37 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.37 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.37 |
| ▸ | PARP3 | Q9Y6F1 | 1/20 | 0.35 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.35 |
| ▸ | SIRT3 | Q9NTG7 | 2/20 | 0.35 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.35 |
| ▸ | TNKS | O95271 | 1/20 | 0.35 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.35 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31662464 | 0.86 | MPO (0.41) | PARP10KMT2AALDH1A1MEN1 | |
| SCHEMBL31662366 | 0.85 | CA1 (0.42) | ALDH1A1 | |
| SCHEMBL31662459 | 0.83 | TBXAS1 (0.40) | PARP10PARP15PARP14KMT2AALDH1A1 | |
| SCHEMBL31662082 | 0.76 | TBXAS1 (0.34) | PARP10PARP15ALDH1A1SIRT2SIRT3 | |
| SCHEMBL31662223 | 0.76 | KDM4E (0.41) | KMT2AALDH1A1MEN1ESR1ESR2 | |
| SCHEMBL31662141 | 0.75 | CPT1A (0.34) | PARP10PARP15PARP2MAP4K4 | |
| SCHEMBL31661965 | 0.75 | SCN9A (0.39) | — | |
| SCHEMBL31661907 | 0.75 | CPT1A (0.34) | PARP10PARP15PARP2MAP4K4 | |
| SCHEMBL31662321 | 0.73 | ESR2 (0.39) | KMT2AALDH1A1F2ESR2 | |
| SCHEMBL31662628 | 0.72 | KCNH2 (0.36) | KMT2AALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025149545-A1 | HETEROARYLPHENYL ETHER DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2025-07-17 | — | — | WO | disclosed |