Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNC | P24863 | 1/20 | 0.41 |
| ▸ | CDK8 | P49336 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | PDK2 | Q15119 | 5/20 | 0.40 |
| ▸ | EGFR | P00533 | 6/20 | 0.39 |
| ▸ | ITK | Q08881 | 4/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31661860 | 0.89 | POLB (0.42) | CCNCCDK8POLBPDK2EGFR | |
| SCHEMBL31661972 | 0.88 | PRKAB2 (0.39) | PDK2 | |
| SCHEMBL31661946 | 0.88 | HRH3 (0.32) | SCN9A | |
| SCHEMBL31662170 | 0.87 | CYP11B2 (0.38) | POLBPDK2SCN9AALDH1A1 | |
| SCHEMBL31662644 | 0.82 | PPARG (0.33) | POLBFFAR1SCN9A | |
| SCHEMBL31662149 | 0.77 | PRKAB2 (0.44) | PDK2ALDH1A1 | |
| SCHEMBL31662132 | 0.77 | CPT2 (0.32) | FFAR1 | |
| SCHEMBL31661965 | 0.76 | SCN9A (0.39) | PDK2SCN9A | |
| SCHEMBL31662147 | 0.75 | CYP11B2 (0.39) | PDK2SCN9A | |
| SCHEMBL31662489 | 0.74 | MAPT (0.34) | POLBFFAR1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025149545-A1 | HETEROARYLPHENYL ETHER DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2025-07-17 | — | — | WO | claimed |
| WO-2025149545-A1 | HETEROARYLPHENYL ETHER DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2025-07-17 | — | — | WO | disclosed |