Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 5/20 | 0.39 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.37 |
| ▸ | HPGDS | O60760 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 8/20 | 0.36 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.35 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | IKBKB | O14920 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31662147 | 0.89 | CYP11B2 (0.39) | SCN9ATBXAS1HRH3CHEK2PDK2 | |
| SCHEMBL31661860 | 0.86 | POLB (0.42) | SCN9AHRH3PDK2OPRM1 | |
| SCHEMBL31662149 | 0.85 | PRKAB2 (0.44) | TBXAS1HRH3PDK2OPRM1IKBKB | |
| SCHEMBL31662459 | 0.82 | TBXAS1 (0.40) | TBXAS1HRH3CHEK2OPRM1 | |
| SCHEMBL31662250 | 0.80 | HRH3 (0.46) | HRH3 | |
| SCHEMBL31661905 | 0.80 | TBXAS1 (0.32) | TBXAS1HRH3CHEK2IKBKB | |
| SCHEMBL31662136 | 0.79 | HRH3 (0.42) | HRH3 | |
| SCHEMBL31662117 | 0.79 | GRM2 (0.35) | TBXAS1HRH3OPRM1 | |
| SCHEMBL31662170 | 0.79 | CYP11B2 (0.38) | SCN9AHRH3PDK2OPRM1 | |
| SCHEMBL31662424 | 0.75 | PARP10 (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025149545-A1 | HETEROARYLPHENYL ETHER DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2025-07-17 | — | — | WO | claimed |
| WO-2025149545-A1 | HETEROARYLPHENYL ETHER DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2025-07-17 | — | — | WO | disclosed |