Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | CCNC | P24863 | 1/20 | 0.41 |
| ▸ | CDK8 | P49336 | 1/20 | 0.41 |
| ▸ | PDK2 | Q15119 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.36 |
| ▸ | ITK | Q08881 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.36 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31661915 | 0.89 | CCNC (0.41) | POLBSMN1; SMN2CCNCCDK8PDK2 | |
| SCHEMBL31662149 | 0.87 | PRKAB2 (0.44) | PDK2ALDH1A1KDM4EHRH3OPRM1 | |
| SCHEMBL31661965 | 0.86 | SCN9A (0.39) | PDK2HRH3SCN9AOPRM1 | |
| SCHEMBL31662147 | 0.85 | CYP11B2 (0.39) | PDK2HRH3SCN9AOPRM1OPRD1 | |
| SCHEMBL31662459 | 0.82 | TBXAS1 (0.40) | POLBALDH1A1KMT2AHRH3OPRM1 | |
| SCHEMBL31661905 | 0.81 | TBXAS1 (0.32) | HRH3 | |
| SCHEMBL31662250 | 0.80 | HRH3 (0.46) | KDM4EHRH3 | |
| SCHEMBL31662117 | 0.77 | GRM2 (0.35) | SMN1; SMN2LMNAALDH1A1KMT2AKDM4E | |
| SCHEMBL31662136 | 0.77 | HRH3 (0.42) | HRH3 | |
| SCHEMBL31662424 | 0.75 | PARP10 (0.48) | CCNCCDK8ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025149545-A1 | HETEROARYLPHENYL ETHER DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2025-07-17 | — | — | WO | claimed |
| WO-2025149545-A1 | HETEROARYLPHENYL ETHER DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2025-07-17 | — | — | WO | disclosed |