Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | PPARD | Q03181 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | ACACB | O00763 | 1/20 | 0.33 |
| ▸ | ACACA | Q13085 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | TTR | P02766 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | FAAH | O00519 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31662594 | 0.87 | MAPT (0.45) | MAPTRAB9ACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL31662198 | 0.84 | CYP1A2 (0.35) | MAPTPOLBACACBACACACYP1A2 | |
| SCHEMBL31662396 | 0.82 | POLB (0.38) | POLBCYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL31662644 | 0.77 | PPARG (0.33) | FFAR1PPARGPOLBTTR | |
| SCHEMBL31661946 | 0.76 | HRH3 (0.32) | — | |
| SCHEMBL31662459 | 0.75 | TBXAS1 (0.40) | POLBCYP3A4CYP2C9TDP1L3MBTL1 | |
| SCHEMBL31662366 | 0.74 | CA1 (0.42) | MAPTPOLBRAB9ACYP1A2CYP3A4 | |
| SCHEMBL31661915 | 0.74 | CCNC (0.41) | FFAR1POLBLMNA | |
| SCHEMBL31662170 | 0.73 | CYP11B2 (0.38) | MAPTPOLB | |
| SCHEMBL31662321 | 0.73 | ESR2 (0.39) | MAPTRAB9ACYP1A2CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025149545-A1 | HETEROARYLPHENYL ETHER DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2025-07-17 | — | — | WO | disclosed |