Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | THPO | P40225 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | GNPAT | O15228 | 2/20 | 0.39 |
| ▸ | TGFBR1 | P36897 | 3/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.35 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.35 |
| ▸ | CPA1 | P15085 | 1/20 | 0.35 |
| ▸ | CPA2 | P48052 | 1/20 | 0.35 |
| ▸ | CPA4 | Q9UI42 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27610443 | 0.81 | KDM4E (0.61) | KDM4EMAPTTHRBALOX15NFKB1 | |
| SCHEMBL21626384 | 0.80 | TGFBR1 (0.42) | KDM4ETGFBR1HIF1ACA1CA2 | |
| SCHEMBL21626383 | 0.80 | TGFBR1 (0.42) | KDM4ETGFBR1HIF1ACA1CA2 | |
| SCHEMBL13394103 | 0.80 | KDM4E (0.43) | KDM4EMAPTTHRBALOX15NFKB1 | |
| SCHEMBL10013379 | 0.80 | KDM4E (0.43) | KDM4EMAPTTHRBALOX15NFKB1 | |
| SCHEMBL11108853 | 0.79 | REN (0.40) | KDM4EMAPTTHRBALOX15NFKB1 | |
| SCHEMBL11108850 | 0.79 | REN (0.40) | KDM4EMAPTTHRBALOX15NFKB1 | |
| SCHEMBL14577477 | 0.78 | ALDH1A1 (0.45) | KDM4EMAPTTHRBALOX15NFKB1 | |
| SCHEMBL9293530 | 0.78 | MAPT (0.38) | KDM4EMAPTTHRBALOX15NFKB1 | |
| SCHEMBL2992278 | 0.78 | KDM4E (0.47) | KDM4EMAPTTHRBALOX15NFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8475765-B2 | Hydroxyalkyl starch derivatives | FRESENIUS KABI DEUTSCHLAND GMBH (DE) | 2013-07-02 | — | — | US | disclosed |
| EP-2143736-B1 | Hydroxyalkyl starch derivatives | FRESENIUS KABI DE GMBH (DE) | 2012-11-07 | — | — | EP | disclosed |
| CN-101133072-B | Hydrogels for controlled release of bioactive materials | FIRMENICH & CIE | 2012-05-30 | — | — | CN | disclosed |
| US-20120046240-A9 | Method of Producing Hydroxyalkyl Starch Derivatives | FRESENIUS KABI DEUTSCHLAND GMBH (DE) | 2012-02-23 | — | — | US | disclosed |
| US-20110054152-A1 | Hydroxyalkyl Starch Derivatives | FRESENIUS KABI DEUTSCHLAND GMBH (DE) | 2011-03-03 | — | — | US | disclosed |
| EP-2272865-A2 | Method of producing hydroxyalkyl starch derivatives | Fresenius Kabi Deutschland GmbH (DE) | 2011-01-12 | — | — | EP | disclosed |
| US-20100317609-A1 | Method of Producing Hydroxyalkyl Starch Derivatives | FRESENIUS KABI DEUTSCHLAND GMBH (DE) | 2010-12-16 | — | — | US | disclosed |
| EP-1863827-B1 | HYDROGELS FOR THE CONTROLLED RELEASE OF BIOACTIVE MATERIALS | FIRMENICH & CIE (CH) | 2010-03-03 | — | — | EP | disclosed |
| EP-2154160-A1 | Hydroxyalkyl starch derivatives | Fresenius Kabi Deutschland GmbH (DE) | 2010-02-17 | — | — | EP | disclosed |
| EP-2143736-A1 | Hydroxyalkyl starch derivatives | Fresenius Kabi Deutschland GmbH (DE) | 2010-01-13 | — | — | EP | disclosed |
| EP-2017287-A2 | Method of producing hydroxyalkyl starch derivatives | Fresenius Kabi Deutschland GmbH (DE) | 2009-01-21 | — | — | EP | disclosed |
| US-20080057005-A1 | HYDROGELS FOR THE CONTROLLED RELEASE OF BIOACTIVE MATERIALS | FIRMENICH SA (CH) | 2008-03-06 | — | — | US | disclosed |
| CN-101133072-A | Hydrogels for controlled release of bioactive materials | FIRMENICH & CIE (CH) | 2008-02-27 | — | — | CN | disclosed |
| EP-1863827-A1 | HYDROGELS FOR THE CONTROLLED RELEASE OF BIOACTIVE MATERIALS | FIRMENICH SA (CH) | 2007-12-12 | — | — | EP | disclosed |
| WO-2006100647-A1 | HYDROGELS FOR THE CONTROLLED RELEASE OF BIOACTIVE MATERIALS | FIRMENICH SA (CH) | 2006-09-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110054152-A1 | Hydroxyalkyl Starch Derivatives | GRHPR, DCXR, HRH2 | KDM4E 4409/4885MAPT 4518/4885THRB 3842/4885 |
| US-20120046240-A9 | Method of Producing Hydroxyalkyl Starch Derivatives | HACL2, HAAO, LIPA | KDM4E 3187/4885MAPT 4440/4885THRB 4762/4885 |
| US-20100317609-A1 | Method of Producing Hydroxyalkyl Starch Derivatives | HACL2, HAAO, LIPA | KDM4E 3187/4885MAPT 4440/4885THRB 4762/4885 |
| US-20080057005-A1 | HYDROGELS FOR THE CONTROLLED RELEASE OF BIOACTIVE MATERIALS | GMPS, CGAS, PDE2A | KDM4E 1558/4885MAPT 4136/4885THRB 2831/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.