Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTK | P33981 | 1/20 | 0.32 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.32 |
| ▸ | CD38 | P28907 | 1/20 | 0.32 |
| ▸ | HTR6 | P50406 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
| ▸ | CSF1R | P07333 | 1/20 | 0.30 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.30 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.30 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31661923 | 0.93 | TTK (0.38) | TTKLRRK2CD38HTR6 | |
| SCHEMBL31661962 | 0.89 | TTK (0.35) | TTKLRRK2CD38HTR6CSF1R | |
| SCHEMBL31661978 | 0.83 | TTK (0.35) | TTKLRRK2CD38 | |
| SCHEMBL31662202 | 0.83 | GSK3B (0.36) | TTKLRRK2CD38HTR6ATM | |
| SCHEMBL31661988 | 0.82 | LRRK2 (0.36) | LRRK2CD38HTR6CSF1RPDGFRB | |
| SCHEMBL31662230 | 0.80 | CD38 (0.34) | LRRK2CD38HTR6ATM | |
| SCHEMBL31662457 | 0.80 | CD38 (0.34) | LRRK2CD38HTR6ATM | |
| SCHEMBL31662100 | 0.78 | — | — | |
| SCHEMBL31662578 | 0.77 | CD38 (0.37) | CD38 | |
| SCHEMBL31662231 | 0.76 | ATM (0.38) | CD38ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025149545-A1 | HETEROARYLPHENYL ETHER DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2025-07-17 | — | — | WO | claimed |
| WO-2025149545-A1 | HETEROARYLPHENYL ETHER DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2025-07-17 | — | — | WO | disclosed |