Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.33 |
| ▸ | CD38 | P28907 | 1/20 | 0.32 |
| ▸ | HTR6 | P50406 | 1/20 | 0.31 |
| ▸ | CSF1R | P07333 | 1/20 | 0.31 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.31 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.31 |
| ▸ | PDE2A | O00408 | 1/20 | 0.31 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.31 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.31 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.31 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.31 |
| ▸ | SYK | P43405 | 1/20 | 0.30 |
| ▸ | BACE1 | P56817 | 1/20 | 0.30 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.30 |
| ▸ | LTA4H | P09960 | 2/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31661923 | 0.84 | TTK (0.38) | LRRK2GSK3BDYRK1ACD38HTR6 | |
| SCHEMBL31661954 | 0.82 | TTK (0.32) | LRRK2CD38HTR6CSF1RPDGFRB | |
| SCHEMBL31661962 | 0.82 | TTK (0.35) | LRRK2CD38HTR6CSF1RPDGFRB | |
| SCHEMBL31662202 | 0.81 | GSK3B (0.36) | LRRK2GSK3BDYRK1ACD38HTR6 | |
| SCHEMBL31662230 | 0.81 | CD38 (0.34) | LRRK2CD38HTR6MAPK14ADORA2A | |
| SCHEMBL31662457 | 0.81 | CD38 (0.34) | LRRK2CD38HTR6TNK2MAPK14 | |
| SCHEMBL31662578 | 0.78 | CD38 (0.37) | CD38SCN9AMAPK14 | |
| SCHEMBL31662072 | 0.78 | SCN9A (0.39) | CD38SCN9AMAPK14 | |
| SCHEMBL31662231 | 0.78 | ATM (0.38) | CD38MAPK14LTA4H | |
| SCHEMBL31662620 | 0.77 | CD38 (0.40) | LRRK2GSK3BDYRK1ACD38MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025149545-A1 | HETEROARYLPHENYL ETHER DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2025-07-17 | — | — | WO | claimed |
| WO-2025149545-A1 | HETEROARYLPHENYL ETHER DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2025-07-17 | — | — | WO | disclosed |