Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK2 | O96017 | 5/20 | 0.48 |
| ▸ | GPR119 | Q8TDV5 | 9/20 | 0.41 |
| ▸ | PDE4A | P27815 | 1/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.38 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | BCDIN3D | Q7Z5W3 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31662385 | 0.93 | CHEK2 (0.41) | CHEK2GPR119PDE4APDE4BPDE4C | |
| SCHEMBL31662466 | 0.91 | CHEK2 (0.40) | CHEK2GPR119PDE4APDE4BPDE4C | |
| SCHEMBL31662540 | 0.91 | GPR119 (0.43) | CHEK2GPR119PDE4APDE4BPDE4C | |
| SCHEMBL31662035 | 0.88 | SCN9A (0.39) | CHEK2 | |
| SCHEMBL31662561 | 0.86 | CHEK2 (0.44) | CHEK2GPR119BCDIN3D | |
| SCHEMBL31662072 | 0.84 | SCN9A (0.39) | CHEK2PDE4D | |
| SCHEMBL31661975 | 0.84 | CHEK2 (0.41) | CHEK2 | |
| SCHEMBL31662506 | 0.82 | MEN1 (0.42) | CHEK2GPR119 | |
| SCHEMBL31661893 | 0.81 | SCN9A (0.38) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL31662085 | 0.81 | SCN9A (0.38) | PDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025149545-A1 | HETEROARYLPHENYL ETHER DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2025-07-17 | — | — | WO | disclosed |