Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | TTK | P33981 | 1/20 | 0.31 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.31 |
| ▸ | PDE2A | O00408 | 1/20 | 0.30 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.30 |
| ▸ | PIM1 | P11309 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31662074 | 0.89 | CYP2D6 (0.36) | CYP3A4CYP2D6CYP2C9GPR119 | |
| SCHEMBL31661943 | 0.87 | L3MBTL1 (0.35) | CYP3A4CYP2D6CYP2C9GPR119 | |
| SCHEMBL31662204 | 0.87 | CYP2D6 (0.36) | CYP3A4CYP2D6CYP2C9GPR119 | |
| SCHEMBL31662621 | 0.85 | GPR119 (0.33) | GPR119 | |
| SCHEMBL31661982 | 0.83 | GPR119 (0.34) | CYP3A4CYP2D6CYP2C9GPR119 | |
| SCHEMBL31661926 | 0.81 | TTK (0.32) | CYP3A4CYP2D6CYP2C9TTK | |
| SCHEMBL31662494 | 0.80 | CA12 (0.36) | CYP3A4CYP2D6CYP2C9GPR119 | |
| SCHEMBL31661961 | 0.78 | PRKAB2 (0.38) | — | |
| SCHEMBL31661899 | 0.75 | HRH3 (0.33) | GPR119 | |
| SCHEMBL31662623 | 0.75 | MAPT (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025149545-A1 | HETEROARYLPHENYL ETHER DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2025-07-17 | — | — | WO | claimed |
| WO-2025149545-A1 | HETEROARYLPHENYL ETHER DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2025-07-17 | — | — | WO | disclosed |