Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.33 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.33 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | PPARA | Q07869 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31662628 | 0.86 | KCNH2 (0.36) | MAPTMEN1KMT2ACHRNB2CHRNB4 | |
| SCHEMBL31662272 | 0.84 | KCNH2 (0.37) | MEN1KMT2ACHRNB2CHRNB4CHRNA3 | |
| SCHEMBL31662394 | 0.83 | CYP11B2 (0.35) | MEN1KMT2ACHRNB2CHRNB4CHRNA3 | |
| SCHEMBL31662464 | 0.82 | MPO (0.41) | MAPTMEN1KMT2AGAAALDH1A1 | |
| SCHEMBL31662398 | 0.79 | BMPR1B (0.34) | ALDH1A1KDM4ENPC1HTT | |
| SCHEMBL31662594 | 0.76 | MAPT (0.45) | MAPTGAAALDH1A1LMNAKDM4E | |
| SCHEMBL31662459 | 0.75 | TBXAS1 (0.40) | KMT2ATBXAS1GAAALDH1A1 | |
| SCHEMBL31661987 | 0.75 | CYP3A4 (0.33) | — | |
| SCHEMBL31662366 | 0.70 | CA1 (0.42) | MAPTGAAALDH1A1LMNAKDM4E | |
| SCHEMBL31662424 | 0.69 | PARP10 (0.48) | MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025149545-A1 | HETEROARYLPHENYL ETHER DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2025-07-17 | — | — | WO | disclosed |