Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRIM24 | O15164 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 7/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 6/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | QPCT | Q16769 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.35 |
| ▸ | RELA | Q04206 | 1/20 | 0.35 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.35 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.35 |
| ▸ | HMOX1 | P09601 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31662299 | 0.85 | JAK3 (0.40) | — | |
| SCHEMBL31662400 | 0.78 | MAOB (0.41) | TRIM24RAB9ASMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL21978806 | 0.77 | ENPP3 (0.51) | RAB9ASMN1; SMN2ALDH1A1POLBNPC1 | |
| SCHEMBL31662171 | 0.77 | TTK (0.36) | — | |
| SCHEMBL31662601 | 0.74 | MEN1 (0.44) | TRIM24RAB9ASMN1; SMN2POLBNPC1 | |
| SCHEMBL31662127 | 0.73 | DGAT1 (0.52) | TRIM24RAB9ASMN1; SMN2NPC1MEN1 | |
| SCHEMBL31662145 | 0.70 | RAB9A (0.39) | RAB9AALDH1A1NPC1QPCT | |
| SCHEMBL31662191 | 0.69 | HRH3 (0.44) | ALDH1A1QPCTLMNA | |
| SCHEMBL31661980 | 0.67 | SCN9A (0.34) | — | |
| SCHEMBL21978557 | 0.66 | HPGDS (0.52) | RAB9ASMN1; SMN2POLBNPC1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025149545-A1 | HETEROARYLPHENYL ETHER DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2025-07-17 | — | — | WO | disclosed |