Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 4/20 | 0.40 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | CASP7 | P55210 | 1/20 | 0.38 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31662347 | 0.87 | LMNA (0.38) | SCN9AKMT2AALDH1A1MEN1LMNA | |
| SCHEMBL31662519 | 0.85 | CA12 (0.41) | SCN9ANPBWR1KMT2AALDH1A1MEN1 | |
| SCHEMBL31662290 | 0.82 | USP2 (0.39) | SCN9ANPBWR1KMT2AALDH1A1LMNA | |
| SCHEMBL31662433 | 0.82 | GLA (0.38) | SCN9ANPBWR1KMT2AALDH1A1KDM4E | |
| SCHEMBL31662527 | 0.80 | MAPT (0.41) | SCN9ANPBWR1KMT2AALDH1A1MEN1 | |
| SCHEMBL31662315 | 0.78 | MAPT (0.41) | SCN9ANPBWR1KMT2AALDH1A1MEN1 | |
| SCHEMBL31662593 | 0.77 | PPARG (0.40) | SCN9ANPBWR1CA12CA1CA2 | |
| SCHEMBL31662262 | 0.76 | LMNA (0.46) | KMT2AMEN1LMNAMAPTHPGD | |
| SCHEMBL29046616 | 0.76 | KDM4E (0.50) | KMT2AALDH1A1MEN1LMNAKDM4E | |
| SCHEMBL31662084 | 0.75 | MAOB (0.36) | LMNAKDM4EMAPTPTPN11TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025149545-A1 | HETEROARYLPHENYL ETHER DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2025-07-17 | — | — | WO | disclosed |