Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA7 | P43166 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31662290 | 0.89 | USP2 (0.39) | USP2NPBWR1ALDH1A1KMT2AKDM4E | |
| SCHEMBL31662294 | 0.88 | HAO1 (0.39) | CA12CA1CA2CA7CA9 | |
| SCHEMBL31662580 | 0.87 | PARP10 (0.46) | ALDH1A1KMT2ASCN9A | |
| SCHEMBL31662404 | 0.85 | SCN9A (0.40) | CA12CA1CA2CA7CA9 | |
| SCHEMBL31662347 | 0.85 | LMNA (0.38) | CA12CA1CA2CA7CA9 | |
| SCHEMBL31662262 | 0.85 | LMNA (0.46) | USP2KMT2AMEN1LMNAMAPT | |
| SCHEMBL31662315 | 0.85 | MAPT (0.41) | USP2NPBWR1ALDH1A1KMT2AKDM4E | |
| SCHEMBL31662527 | 0.85 | MAPT (0.41) | USP2NPBWR1ALDH1A1KMT2AKDM4E | |
| SCHEMBL31662433 | 0.84 | GLA (0.38) | CA12CA1CA2CA7CA9 | |
| SCHEMBL31662084 | 0.84 | MAOB (0.36) | CA12CA1CA2CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025149545-A1 | HETEROARYLPHENYL ETHER DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2025-07-17 | — | — | WO | disclosed |