SCHEMBL31662288

SCHEMBL31662288

Cn1ncc2cc(C(N)=O)cc(Oc3ccc(O)cc3F)c21

nearest known ligand 0.41

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
AR P10275 3/20 0.40
SCN9A Q15858 7/20 0.38
MAOB P27338 2/20 0.34
BRD4 O60885 1/20 0.34
MAPK14 Q16539 3/20 0.34
MAOA P21397 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31662084 0.88 MAOB (0.36) MAOBBRD4MAOA
SCHEMBL31662580 0.84 PARP10 (0.46) ARSCN9A
SCHEMBL31662603 0.82 SCN9A (0.38) ARSCN9A
SCHEMBL31662381 0.81 SCN9A (0.37) ARSCN9A
SCHEMBL31662520 0.78 AR (0.40) ARSCN9AMAOBMAPK14MAOA
SCHEMBL31661921 0.78 TLR7 (0.42)
SCHEMBL31662433 0.75 GLA (0.38) SCN9AMAOBMAOA
SCHEMBL31662294 0.73 HAO1 (0.39) SCN9A
SCHEMBL31662377 0.72 SCN9A (0.43) SCN9A
SCHEMBL31662519 0.71 CA12 (0.41) SCN9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025149545-A1 HETEROARYLPHENYL ETHER DERIVATIVES F. HOFFMANN-LA ROCHE AG (CH) 2025-07-17 WO disclosed