Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 2/20 | 0.36 |
| ▸ | MAOB | P27338 | 2/20 | 0.36 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | TTR | P02766 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | CA7 | P43166 | 2/20 | 0.35 |
| ▸ | CA9 | Q16790 | 2/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31662084 | 0.87 | MAOB (0.36) | MAOAMAOBCYP3A4KDM4ECA12 | |
| SCHEMBL31662519 | 0.84 | CA12 (0.41) | KMT2ACYP3A4KDM4EALDH1A1NPBWR1 | |
| SCHEMBL31662404 | 0.82 | SCN9A (0.40) | GLAKMT2AMAOAMAOBACHE | |
| SCHEMBL31662290 | 0.76 | USP2 (0.39) | KMT2AKDM4EALDH1A1NPBWR1USP2 | |
| SCHEMBL31662347 | 0.75 | LMNA (0.38) | KMT2AMAOAMAOBCYP3A4KDM4E | |
| SCHEMBL31662288 | 0.75 | AR (0.40) | MAOAMAOBSCN9A | |
| SCHEMBL31662527 | 0.74 | MAPT (0.41) | KMT2ACYP3A4KDM4EALDH1A1NPBWR1 | |
| SCHEMBL29046616 | 0.74 | KDM4E (0.50) | KMT2AKDM4EALDH1A1CA12CA1 | |
| SCHEMBL24408046 | 0.74 | KMT2A (0.46) | GLAKMT2ATTRCYP3A4ALDH1A1 | |
| SCHEMBL31662315 | 0.72 | MAPT (0.41) | KMT2AKDM4EALDH1A1NPBWR1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025149545-A1 | HETEROARYLPHENYL ETHER DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2025-07-17 | — | — | WO | disclosed |