Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 2/20 | 0.39 |
| ▸ | CHRM5 | P08912 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | RORC | P51449 | 1/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.32 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.32 |
| ▸ | CASP7 | P55210 | 1/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31662446 | 0.91 | ALDH1A1 (0.35) | CASP3CHRM5ALDH1A1MAPTMEN1 | |
| SCHEMBL31662418 | 0.90 | PARP1 (0.35) | CASP3CHRM5ALDH1A1MAPTMEN1 | |
| SCHEMBL31662770 | 0.78 | CD38 (0.36) | MAPTRORCOPRK1 | |
| SCHEMBL31662611 | 0.76 | PDE4B (0.36) | MAPTMEN1KMT2ARORCOPRK1 | |
| SCHEMBL17888595 | 0.75 | MAPT (0.44) | ALDH1A1MAPTMEN1KMT2ATDP1 | |
| SCHEMBL31662261 | 0.75 | MAPT (0.34) | MAPTTDP1RORCESR2OPRK1 | |
| SCHEMBL31662303 | 0.75 | CHEK1 (0.39) | MAPTRORC | |
| SCHEMBL31662302 | 0.75 | CHEK1 (0.39) | MAPTRORC | |
| SCHEMBL31662238 | 0.75 | CYP1A2 (0.33) | ALDH1A1MAPTKMT2APOLBLMNA | |
| SCHEMBL31662538 | 0.74 | OPRK1 (0.33) | MAPTRORCESR2OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025149545-A1 | HETEROARYLPHENYL ETHER DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2025-07-17 | — | — | WO | disclosed |