Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.35 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.35 |
| ▸ | PRKAB2 | O43741 | 3/20 | 0.35 |
| ▸ | PRKAG1 | P54619 | 3/20 | 0.35 |
| ▸ | PRKAA2 | P54646 | 3/20 | 0.35 |
| ▸ | PRKAA1 | Q13131 | 3/20 | 0.35 |
| ▸ | PRKAG3 | Q9UGI9 | 3/20 | 0.35 |
| ▸ | PRKAG2 | Q9UGJ0 | 3/20 | 0.35 |
| ▸ | PRKAB1 | Q9Y478 | 3/20 | 0.35 |
| ▸ | CASP3 | P42574 | 2/20 | 0.35 |
| ▸ | CASP7 | P55210 | 2/20 | 0.35 |
| ▸ | MIF | P14174 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31662418 | 0.92 | PARP1 (0.35) | ALDH1A1MAPTKMT2AMEN1POLB | |
| SCHEMBL31662399 | 0.91 | CASP3 (0.39) | ALDH1A1MAPTKMT2AMEN1POLB | |
| SCHEMBL31662428 | 0.78 | DHODH (0.37) | PRKAB2PRKAG1PRKAA2PRKAA1PRKAG3 | |
| SCHEMBL31662238 | 0.76 | CYP1A2 (0.33) | ALDH1A1MAPTKMT2APOLBLMNA | |
| SCHEMBL31662475 | 0.76 | GCK (0.34) | MIFKDM4EDHODH | |
| SCHEMBL31662331 | 0.73 | DHODH (0.36) | MIFDHODH | |
| SCHEMBL17899132 | 0.72 | MAPT (0.41) | ALDH1A1MAPTKMT2AMEN1POLB | |
| SCHEMBL17931463 | 0.72 | ALDH1A1 (0.42) | ALDH1A1MAPTL3MBTL1KDM4E | |
| SCHEMBL31662332 | 0.72 | MIF (0.34) | KMT2AMEN1SMN1; SMN2PRKAB2PRKAG1 | |
| SCHEMBL31661945 | 0.70 | LRRK2 (0.36) | ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025149545-A1 | HETEROARYLPHENYL ETHER DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2025-07-17 | — | — | WO | disclosed |