Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 9/20 | 0.40 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31662506 | 0.92 | MEN1 (0.42) | GPR119CHEK2MAPTALDH1A1 | |
| SCHEMBL31662561 | 0.91 | CHEK2 (0.44) | GPR119CHEK2 | |
| SCHEMBL31662466 | 0.86 | CHEK2 (0.40) | GPR119CHEK2TP53MAPT | |
| SCHEMBL31662770 | 0.84 | CD38 (0.36) | MAPT | |
| SCHEMBL31662385 | 0.81 | CHEK2 (0.41) | GPR119CHEK2MAPTALDH1A1 | |
| SCHEMBL31661986 | 0.80 | CHEK2 (0.40) | CHEK2ALDH1A1 | |
| SCHEMBL31662592 | 0.80 | CHEK2 (0.48) | GPR119CHEK2CYP3A4 | |
| SCHEMBL31662101 | 0.80 | MAPT (0.38) | MAPTALDH1A1 | |
| SCHEMBL31661960 | 0.79 | SCN1A (0.37) | CHEK2MAPTALDH1A1 | |
| SCHEMBL31662113 | 0.79 | SCN9A (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025149545-A1 | HETEROARYLPHENYL ETHER DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2025-07-17 | — | — | WO | disclosed |