Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK2 | O96017 | 2/20 | 0.41 |
| ▸ | GPR119 | Q8TDV5 | 10/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | PDE4A | P27815 | 2/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31662592 | 0.93 | CHEK2 (0.48) | CHEK2GPR119PDE4APDE4BPDE4C | |
| SCHEMBL31662466 | 0.92 | CHEK2 (0.40) | CHEK2GPR119MAPTPDE4APDE4B | |
| SCHEMBL31662506 | 0.85 | MEN1 (0.42) | CHEK2GPR119KDM4EMEN1USP2 | |
| SCHEMBL31662540 | 0.84 | GPR119 (0.43) | CHEK2GPR119PDE4APDE4BPDE4C | |
| SCHEMBL31662578 | 0.84 | CD38 (0.37) | KDM4EMEN1ALDH1A1GAAKMT2A | |
| SCHEMBL31662561 | 0.82 | CHEK2 (0.44) | CHEK2GPR119 | |
| SCHEMBL31662484 | 0.81 | GPR119 (0.40) | CHEK2GPR119ALDH1A1MAPT | |
| SCHEMBL31662035 | 0.81 | SCN9A (0.39) | CHEK2ALDH1A1MAPT | |
| SCHEMBL7399145 | 0.80 | GPR119 (0.56) | CHEK2GPR119KDM4EMEN1KMT2A | |
| SCHEMBL31662006 | 0.77 | GCK (0.43) | MEN1ALDH1A1HPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025149545-A1 | HETEROARYLPHENYL ETHER DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2025-07-17 | — | — | WO | disclosed |