Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | ALPL | P05186 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.34 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31662489 | 0.87 | MAPT (0.34) | MAPTRAB9AL3MBTL1TDP1LMNA | |
| SCHEMBL31662459 | 0.87 | TBXAS1 (0.40) | L3MBTL1TDP1ALDH1A1GAACYP2C9 | |
| SCHEMBL31662366 | 0.84 | CA1 (0.42) | MAPTRAB9AL3MBTL1TDP1ALDH1A1 | |
| SCHEMBL31662321 | 0.82 | ESR2 (0.39) | MAPTRAB9AALDH1A1MAPK1LMNA | |
| SCHEMBL31662277 | 0.82 | MAPT (0.38) | MAPTRAB9AL3MBTL1TDP1ALDH1A1 | |
| SCHEMBL31662491 | 0.80 | HRH3 (0.42) | ALDH1A1KDM4E | |
| SCHEMBL31662628 | 0.79 | KCNH2 (0.36) | MAPTRAB9AL3MBTL1ALDH1A1MAPK1 | |
| SCHEMBL31662394 | 0.77 | CYP11B2 (0.35) | LMNASMN1; SMN2GAA | |
| SCHEMBL31662623 | 0.76 | MAPT (0.33) | MAPTRAB9AALDH1A1MAPK1LMNA | |
| SCHEMBL31662272 | 0.75 | KCNH2 (0.37) | RAB9AL3MBTL1ALDH1A1MAPK1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025149545-A1 | HETEROARYLPHENYL ETHER DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2025-07-17 | — | — | WO | disclosed |